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Very hard to change, because you don even know you doing it,
Human isolated red blood cells (RBCs) and platelets as sources of UDP glucose were investigated. Hypoxia induced release of UDP glucose from porcine coronary arteries was also investigated. The function of the P2Y14 receptor as an anti/pro inflammatory stimulus in porcine coronary arteries was also explored.Results: UDP glucose steroids, UDP N acetylglucosamine and UDP glucuronic acid elicited concentration dependent contractions in the porcine coronary artery; MRS2690 induced contractions were 10 fold more potent than those of the UDP sugars.
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